From Proximity Mapping to Therapeutics: Rational Target-Pair Selection With the MINTTM Platform for Bispecific ADCs
9:00 am - Tuesday 9th June 2026
- Explore how MINT™ maps cell-surface protein microenvironments using proximity proteomics and machine learning to identify novel, co-localized target pairs for precision therapeutics
- Outline how applying MINT™ enables rational selection of tumor-associated proximity antigens (TAPAs), guiding the design of bispecific ADCs with improved tumor selectivity and reduced offtarget engagement
- Analyze how this proximity-driven framework supports the discovery and optimization of multiple bispecific ADC candidates, providing a systematic path from target-pair identification to preclinical validation
