In Vitro & In Vivo Preclinical Evaluation of Antibody-Drug Conjugates
- Explore how in vitro assays can facilitate lead candidate selection through pharmacodynamic analysis
- Discuss how to evaluate the bystander effect of ADCs using in vivo mouse models, and how model selection impacts the pharmacokinetic profile of ADCs
- Showcase how in vivo mouse models can reveal clinically relevant drug resistance mechanisms to Enhertu