In Vitro & In Vivo Preclinical Evaluation of Antibody-Drug Conjugates

• Explore how in vitro assays can facilitate lead candidate selection through pharmacodynamic analysis
• Discuss how to evaluate the bystander effect of ADCs using in vivo mouse models, and how model selection impacts the pharmacokinetic profile of ADCs
• Showcase how in vivo mouse models can reveal clinically relevant drug resistance mechanisms to Enhertu

Speakers:

Jianming Xu

Head of Immuno-Oncology Team

GemPharmatech